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III. The Full Cardiovascular Model
The previous exercises looked at the impact of the various parameters of ventricular performance on the left ventricle alone. The "full model" places the left ventricle back into the circulatory loop (where it
belongs!). The major difference is that changes in a single parameter
will now affect other parameters. For example, by changing left
ventricular afterload, the output of the ventricle is reduced, thus
reducing venous return to the heart and hence also reducing preload! You
should explore how changing clinically relevant parameters (such as blood
volume, heart rate, vascular resistance, etc.) affect overall
cardiovascular function (such as systemic blood pressure, cardiac output,
filling pressures, etc.).