Cardiac Mechanics Simulator Tutorial

Exercise Set 1

Introduction
Pressure-Volume Loop Basics
Identify Events on the P-V Loop
Examine P-V Variables Under Normal Conditions
Examine the Effect of Varying Preload
Varying the Contractility of the Ventricle
Varying the Afterload
Examine the Effect of Varying the Heart Rate
Valve Pathologies
Mitral Regurgitation
Mitral Stenosis
Aortic Regurgitation
Aortic Stenosis
The Frank-Starling Law
The Full Cardiovascular Model
Resources

III. The Full Cardiovascular Model

The previous exercises looked at the impact of the various parameters of ventricular performance on the left ventricle alone. The "full model" places the left ventricle back into the circulatory loop (where it belongs!). The major difference is that changes in a single parameter will now affect other parameters. For example, by changing left ventricular afterload, the output of the ventricle is reduced, thus reducing venous return to the heart and hence also reducing preload! You should explore how changing clinically relevant parameters (such as blood volume, heart rate, vascular resistance, etc.) affect overall cardiovascular function (such as systemic blood pressure, cardiac output, filling pressures, etc.).


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Filling Pressure 0 for full vircuit Threshold for Elastance/MAP effect is off. Was set to 50.0 Threshold for Elastance/MAP RV difference with total below added to volCsv (optional)

 

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